Salary Data

Data Scientist Salary in St. Louis

$117,000

median salary, 10% below the national average

According to Orbit's 2026 salary analysis, the average Data Scientist salary in St. Louis is $117,000. Salaries range from $90,000 (25th percentile) to $151,000 (75th percentile), adjusted for St. Louis's cost of living.

Get Your Salary Playbook

Salary range

25th Percentile

$90,000

per year

Median

$117,000

per year

75th Percentile

$151,000

per year

How St. Louis compares

St. Louis, MO

$117,000

Cost of living: 10% below average

National Average

$130,000

St. Louis is $13,000 below

Data Scientist job market in St. Louis

St. Louis market overview

St. Louis offers one of the most affordable major metro areas in the country, with a strong base in healthcare, financial services, and manufacturing. The region's anchor employers include Boeing, Centene, and Washington University's medical campus. A growing biotech and plant sciences corridor centered on the Cortex Innovation District is attracting new investment and talent.

What drives Data Scientist salaries

Statistical depth, industry vertical, and the ability to translate models into business impact are the biggest levers. Data scientists who can deploy production ML models earn significantly more than those focused solely on analysis. Specialization in NLP, computer vision, or causal inference commands additional premiums.

Beyond base salary

Total compensation

Equity grants at tech companies add $20,000 to $100,000+ annually, especially at ML focused firms. Bonuses of 10 to 20% are standard. Some companies offer research stipends, conference travel budgets, and compute credits as additional perks.

Tax considerations in St. Louis

Missouri's top income tax rate is about 4.8%, and St. Louis City adds a 1% earnings tax. The low base cost of living means your after tax salary still stretches further than in most metros.

Career progression

Entry level data scientists with a master's degree start at $95,000 to $120,000. Mid level roles reach $130,000 to $170,000 after three years. Senior data scientists earn $170,000 to $220,000, while principal or staff level scientists at top firms exceed $250,000 in total compensation.

Top industries in St. Louis

HealthcareDefense & AerospaceFinancial ServicesPlant Sciences & BiotechManufacturing

Negotiating in St. Louis

Emphasize your willingness to work in person at Cortex or the BJC campus. St. Louis employers offer higher packages for candidates who commit to the local innovation hubs.

Data Scientist salary FAQ

A PhD adds roughly $15,000 to $30,000 to starting salary and opens doors to research scientist roles that require deep specialization. However, the three to five years spent in a PhD program represent significant opportunity cost. Industry experience can close this gap over time.

Machine learning engineering and deep learning specializations currently command the highest premiums, followed by NLP and computer vision. Data scientists who can own the full pipeline from research to production deployment are especially valuable and can negotiate 20 to 30% above standard offers.

St. Louis offers competitive compensation for Data Scientists relative to its cost of living. The local job market, industry presence, and quality of life all factor into whether St. Louis is the right fit. Consider using Orbit's Salary Playbook to compare offers across cities and factor in your personal financial situation.

Start by understanding the market range: $90,000 to $151,000 for Data Scientists in St. Louis. Research the specific company, prepare data points about your experience, and consider total compensation including equity, bonuses, and benefits. Orbit's Salary Playbook provides personalized negotiation strategies based on your specific offer.

Data Scientist salary in other cities

Other salaries in St. Louis

More resources

Negotiating a Data Scientist offer?

Get a personalized Salary Playbook with negotiation strategies tailored to your offer, experience, and financial runway.

Get Started Free