Salary Data
Data Scientist Salary in St. Louis
$117,000
median salary, 10% below the national average
According to Orbit's 2026 salary analysis, the average Data Scientist salary in St. Louis is $117,000. Salaries range from $90,000 (25th percentile) to $151,000 (75th percentile), adjusted for St. Louis's cost of living.
Salary range
How St. Louis compares
St. Louis, MO
$117,000
Cost of living: 10% below average
National Average
$130,000
St. Louis is $13,000 below
Data Scientist job market in St. Louis
St. Louis market overview
St. Louis offers one of the most affordable major metro areas in the country, with a strong base in healthcare, financial services, and manufacturing. The region's anchor employers include Boeing, Centene, and Washington University's medical campus. A growing biotech and plant sciences corridor centered on the Cortex Innovation District is attracting new investment and talent.
What drives Data Scientist salaries
Statistical depth, industry vertical, and the ability to translate models into business impact are the biggest levers. Data scientists who can deploy production ML models earn significantly more than those focused solely on analysis. Specialization in NLP, computer vision, or causal inference commands additional premiums.
Beyond base salary
Total compensation
Equity grants at tech companies add $20,000 to $100,000+ annually, especially at ML focused firms. Bonuses of 10 to 20% are standard. Some companies offer research stipends, conference travel budgets, and compute credits as additional perks.
Tax considerations in St. Louis
Missouri's top income tax rate is about 4.8%, and St. Louis City adds a 1% earnings tax. The low base cost of living means your after tax salary still stretches further than in most metros.
Career progression
Entry level data scientists with a master's degree start at $95,000 to $120,000. Mid level roles reach $130,000 to $170,000 after three years. Senior data scientists earn $170,000 to $220,000, while principal or staff level scientists at top firms exceed $250,000 in total compensation.
Top industries in St. Louis
Negotiating in St. Louis
Emphasize your willingness to work in person at Cortex or the BJC campus. St. Louis employers offer higher packages for candidates who commit to the local innovation hubs.